Publications utilising samples and/or data from the UKLWC biobank

There have so far been more than 60 publications utilising samples and/or data from the UKLWC biobank

Grouped by year of publication

  1. Burnell M, Gentry-Maharaj A, Skates SJ, Ryan A, Karpinskyj C, Kalsi J, Apostolidou S, Singh N, Dawnay A, Woolas R, Fallowfield L, Campbell S, McGuire A, Jacobs IJ, Parmar M, Menon U. UKCTOCS update: applying insights of delayed effects in cancer screening trials to the long-term follow-up mortality analysis. Trials. 2021 Mar 1;22(1):173. doi: 10.1186/s13063-021-05125-8. PMID: 33648562; PMCID: PMC7919310.
  2. Kalsi J, Gentry-Maharaj A, Ryan A, Singh N, Burnell M, Massingham S, Apostolidou S, Sharma A, Williamson K, Seif M, Mould T, Woolas R, Dobbs S, Leeson S, Fallowfield L, Skates SJ, Parmar M, Campbell S, Jacobs I, McGuire A, Menon U. Performance Characteristics of the Ultrasound Strategy during Incidence Screening in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Cancers (Basel). 2021 Feb 18;13(4):858. doi: 10.3390/cancers13040858. PMID: 33670571; PMCID: PMC7922843.
  3. Kalsi JK, Ryan A, Gentry-Maharaj A, Margolin-Crump D, Singh N, Burnell M, Benjamin E, Apostolidou S, Habib M, Massingham S, Karpinskyj C, Woolas R, Widschwendter M, Fallowfield L, Campbell S, Skates S, McGuire A, Parmar M, Jacobs I, Menon U. Completeness and accuracy of national cancer and death registration for outcome ascertainment in trials-an ovarian cancer exemplar. Trials. 2021 Jan 25;22(1):88. doi: 10.1186/s13063-020-04968-x. PMID: 33494753; PMCID: PMC7831170.

Gentry-Maharaj A, Blyuss O, Ryan A, Burnell M, Karpinskyj C, Gunu R, Kalsi JK, Dawnay A, Marino IP, Manchanda R, Lu K, Yang WL, Timms JF, Parmar M, Skates SJ, Bast RC Jr, Jacobs IJ, Zaikin A, Menon U. Multi-Marker Longitudinal Algorithms Incorporating HE4 and CA125 in Ovarian Cancer Screening of Postmenopausal Women. Cancers (Basel). 2020 Jul 17;12(7):1931. doi: 10.3390/cancers12071931. PMID: 32708856; PMCID: PMC7409061.

• Trembling PM, Apostolidou S, Gentry-Maharaj A, Parkes J, Ryan A, Tanwar S, Burnell M, Harris S, Menon U, Rosenberg WM. The Enhanced Liver Fibrosis test is associated with liver-related outcomes in postmenopausal women with risk factors for liver disease. BMC Gastroenterol. 2020 Apr 15;20(1):104. doi: 10.1186/s12876-020-01251-w. PMID: 32293289; PMCID: PMC7158048.

Borges MC, Schmidt AF, Jefferis B, Wannamethee SG, Lawlor DA, Kivimaki M, Kumari M, Gaunt TR, Ben-Shlomo Y, Tillin T, Menon U, Providencia R, Dale C, Gentry-Maharaj A, Hughes A, Chaturvedi N, Casas JP, Hingorani AD; UCLEB Consortium**. Circulating Fatty Acids and Risk of Coronary Heart Disease and Stroke: Individual Participant Data Meta-Analysis in Up to 16 126 Participants. J Am Heart Assoc. 2020 Mar 3;9(5):e013131. doi: 10.1161/JAHA.119.013131. Epub 2020 Mar 2. PMID: 32114887; PMCID: PMC7335585.

Whitwell HJ, Worthington J, Blyuss O, Gentry-Maharaj A, Ryan A, Gunu R, Kalsi J, Menon U, Jacobs I, Zaikin A, Timms JF. Improved early detection of ovarian cancer using longitudinal multimarker models. Br J Cancer. 2020 Mar;122(6):847-856. doi: 10.1038/s41416-019-0718-9. Epub 2020 Jan 15. PMID: 31937926; PMCID: PMC7078315.

Gentry-Maharaj A, Burnell M, Dilley J, Ryan A, Karpinskyj C, Gunu R, Mallett S, Deeks J, Campbell S, Jacobs I, Sundar S, Menon U. Serum HE4 and diagnosis of ovarian cancer in postmenopausal women with adnexal masses. Am J Obstet Gynecol. 2020 Jan;222(1):56.e1-56.e17. doi: 10.1016/j.ajog.2019.07.031. Epub 2019 Jul 24. PMID: 31351062; PMCID: PMC7471839.

  • Valbuena GN, Apostolidou S, Roberts R, Barnes J, Alderton W, Harper L, Jacobs I, Menon U, Keun HC. The 14q32 maternally imprinted locus is a major source of longitudinally stable circulating microRNAs as measured by small RNA sequencing. Sci Rep. 2019 Oct 31;9(1):15787. doi: 10.1038/s41598-019-51948-6.
  • Geary B, Walker MJ, Snow JT, Lee DCH, Pernemalm M, Maleki-Dizaji S, Azadbakht N, Apostolidou S, Barnes J, Krysiak P, Shah R, Booton R, Dive C, Crosbie PA, Whetton AD. Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients. J Proteome Res. 2019 Sep 6;18(9):3369-3382. doi: 10.1021/acs.jproteome.9b00287. Epub 2019 Aug 21.PMID: 31408348
  • Russell MR, Graham C, D'Amato A, Gentry-Maharaj A, Ryan A, Kalsi JK, Whetton AD, Menon U, Jacobs I, Graham RLJ. Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel. Br J Cancer. 2019 Aug 7. doi: 10.1038/s41416-019-0544-0. PMID: 31388184
  • Gentry-Maharaj A, Burnell M, Dilley J, Ryan A, Karpinskyj C, Gunu R, Mallett S, Deeks J, Campbell S, Jacobs I, Sundar S, Menon U. Serum HE4 and diagnosis of ovarian cancer in postmenopausal women with adnexal masses. American Journal of Obstetrics and Gynecology. 2019 Jul 24. doi.org:10.1016/j.ajog.2019.07.031 PMID: 31351062
  • Simmons AR, Fourkala EO, Gentry-Maharaj A, Ryan A, Sutton MN, Baggerly K, Zheng H, Lu KH, Jacobs I, Skates S, Menon U, Bast RC. Complementary longitudinal serum biomarkers to CA125 for early detection of ovarian cancer. Cancer Prev Res (Phila). 2019 Apr 9. pii: canprevres.0377.2018. doi: 10.1158/1940-6207.CAPR-18-0377. PMID: 30967390.
  • Jin, Z., Collier, T. S., Dai, D. L. Y., Chen, V., Hollander, Z., Ng, R. T, McManus BM, Balshaw R, Apostolidou, S, Penny, MS, Bystrom, C. Development and Validation of Apolipoprotein AI-Associated Lipoprotein Proteome Panel for the Prediction of Cholesterol Efflux Capacity and Coronary Artery Disease. Clin Chem. 2019 Feb; 65(2):282-290. doi: 10.1373/clinchem.2018.291922. Epub 2018 Nov 21.
  • Thomas DS, Gentry-Maharaj A, Ryan A, Fourkala EO, Apostolidou S, Burnell M, Alderton W, Barnes J, Timms JF, Menon U. Colorectal cancer ascertainment through cancer registries, hospital episode statistics, and self-reporting compared to confirmation by clinician: A cohort study nested within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Cancer Epidemiol. 2019 Jan 4;58:167-174. doi: 10.1016/j.canep.2018.11.011. PMID 30616086.
  • Vázquez MA, Mariño IP, Blyuss O, Ryan A, Gentry-Maharaj A, Kalsi J, Manchanda R, Jacobs I, Menon U, Zaikin A. A quantitative performance study of two automatic methods for the diagnosis of ovarian cancer. Biomedical Signal Processing and Control. 2018 Sep 1. 46 pp. 86-93. doi: 10.1016/j.bspc.2018.07.001. PMID: 30245736
  • Blyuss O, Burnell M, Ryan A, Gentry-Maharaj A, Marino I, Kalsi J, Manchanda R, Timms J, Parmar M, Skates S, Jacobs I, Zaikin A, Menon U. Comparison of longitudinal CA125 algorithms as a first line screen for ovarian cancer in the general population. Clin Cancer Res. 2018 Jul 3. pii: clincanres.0208.2018. doi: 10.1158/1078-0432.CCR-18-0208. [Epub ahead of print] PMID: 30084833
  • Yang X, Leslie G, Gentry-Maharaj A, Ryan A, Intermaggio M, Lee A, Kalsi JK, Tyrer J, Gaba F, Manchanda R, Pharoah PDP, Gayther SA, Ramus SJ, Jacobs I, Menon U, Antoniou AC. Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study. J Med Genet. 2018 May 5. pii: jmedgenet-2018-105313. doi: 10.1136/jmedgenet-2018-105313. [Epub ahead of print] PubMed PMID: 29730597.
  • Whitwell HJ, Blyuss O, Menon U, Timms JF, Zaikin A. Parenclitic networks for predicting ovarian cancer. Oncotarget. 2018 Apr 27;9(32):22717-22726. doi: 10.18632/oncotarget.25216. eCollection 2018 Apr 27. PMID: 29854310.
  • Cuenco J, Wehnert N, Blyuss O, Kazarian A, Whitwell HJ, Menon U, Dawnay A, Manns MP, Pereira SP, Timms JF. Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis. Oncotarget. 2018 Apr 3. 9(25):17430-17442. doi: 10.18632/oncotarget.24732. eCollection 2018 Apr 3. PubMed PMID: 29707118.
  • Trembling PM, Apostolidou S, Gentry-Maharaj A, Parkes J, Ryan A, Tanwar S, Burnell M, Menon U*, Rosenberg WM*. Association between skirt size and chronic liver disease in post-menopausal women: a prospective cohort study within the United Kingdom Trial of Ovarian Cancer Screening (UKCTOCS). BMC Public Health. 2018 Mar 27;18(1):409. doi: 10.1186/s12889-018-5308-x. PubMed PMID: 29587697; PubMed Central PMCID: PMC5870222.* contributed equally
  • Widschwendter M*, Zikan M*, Wahl B*, Lempiäinen H, Paprotka T, Evans I, Jones A, Ghazali S, Reisel D, Eichner J, Rujan T, Yang Z, Teschendorff AE, Ryan A, Cibula D, Menon U*, Wittenberger T*. The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer. Genome Med. 2017 Dec 22;9(1):116. doi: 10.1186/s13073-017-0500-7. PubMed PMID: 29268796. * equal contribution
  • Widschwendter M, Evans I, Jones A, Ghazali S, Reisel D, Ryan A, Gentry-Maharaj A, Zikan M, Cibula D, Eichner J, Alunni-Fabbroni M, Koch J, Janni WJ, Paprotka T, Wittenberger T, Menon U, Wahl B, Rack B, Lempiäinen H. Methylation patterns in serum DNA for early identification of disseminated breast cancer. Genome Med. 2017 Dec 22;9(1):115. doi: 10.1186/s13073-017-0499-9. PubMed PMID: 29268762.
  • Krishnan S, Whitwell HJ, Cuenco J, Gentry-Maharaj A, Menon U, Pereira SP, Gaspari M, Timms JF. Evidence of Altered Glycosylation of Serum Proteins Prior to Pancreatic Cancer Diagnosis. Int J Mol Sci. 2017 Dec 9;18(12). pii: E2670. doi: 10.3390/ijms18122670. PubMed PMID: 29232830.
  • Borges MC, Barros AJD, Ferreira DLS, Casas JP, Horta BL, Kivimaki M, Kumari M, Menon U, Gaunt TR, Ben-Shlomo Y, Freitas DF, Oliveira IO, Gentry-Maharaj A, Fourkala E, Lawlor DA, Hingorani AD. Metabolic Profiling of Adiponectin Levels in Adults: Mendelian Randomization Analysis. Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001837. doi: 10.1161/CIRCGENETICS.117.001837. PubMed PMID: 29237687; PubMed Central PMCID: PMC5736126.
  • Yang WL, Gentry-Maharaj A, Simmons A, Ryan A, Fourkala EO, Lu Z, Baggerly KA, Zhao Y, Lu KH, Bowtell D, Jacobs I, Skates SJ, He WW, Menon U*, Bast RC* Jr; AOCS Study Group. Elevation of TP53 Autoantibody Before CA125 in Preclinical Invasive Epithelial Ovarian Cancer. Clin Cancer Res. 2017 Oct 1;23(19):5912-5922. doi: 10.1158/1078-0432.CCR-17-0284. Epub 2017 Jun 21. PubMed PMID: 28637689; PubMed Central PMCID: PMC5626590. * equal contribution
  • Russell MR, Graham C, D'Amato A, Gentry-Maharaj A, Ryan A, Kalsi JK, Ainley C, Whetton AD, Menon U, Jacobs I, Graham RLJ. A combined biomarker panel shows improved sensitivity for the early detection of ovarian cancer allowing the identification of the most aggressive type II tumours. Br J Cancer. 2017 Aug 22;117(5):666-674. doi: 10.1038/bjc.2017.199. Epub 2017 Jun 29. PubMed PMID: 28664912; PubMed Central PMCID: PMC5572165.
  • Stott W, Campbell S, Franchini A, Blyuss O, Zaikin A, Ryan A, Jones C, Gentry-Maharaj A, Fletcher G, Kalsi J, Skates S, Parmar M, Amso N, Jacobs I, Menon U. Self-reported transvaginal ultrasound visualization of normal ovaries in postmenopausal women is not reliable: results of expert review of archived images in UKCTOCS. Ultrasound Obstet Gynecol. 2017 Aug 10. doi: 10.1002/uog.18836. [Epub ahead of print] PubMed PMID: 28796383.
  • Trembling PM, Apostolidou S, Gentry-Maharaj A, Parkes J, Ryan A, Tanwar S, Burnell M, Jacobs I, Menon U*, Rosenberg WM*. Risk of chronic liver disease in post-menopausal women due to body mass index, alcohol and their interaction: a prospective nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMC Public Health. 2017 Jun 28;17(1):603. doi: 10.1186/s12889-017-4518-y. PubMed PMID: 28659136; PubMed Central PMCID: PMC5490218. * equal contribution
  • Dale CE, Fatemifar G, Palmer TM, White J, Prieto-Merino D, Zabaneh D, Engmann JEL, Shah T, Wong A, Warren HR, McLachlan S, Trompet S, Moldovan M, Morris RW, Sofat R, Kumari M, Hyppönen E, Jefferis BJ, Gaunt TR, Ben-Shlomo Y, Zhou A, Gentry-Maharaj A, Ryan A; UCLEB Consortium; METASTROKE Consortium, Mutsert R, Noordam R, Caulfield MJ, Jukema JW, Worrall BB, Munroe PB, Menon U, Power C, Kuh D, Lawlor DA, Humphries SE, Mook-Kanamori DO, Sattar N, Kivimaki M, Price JF, Davey Smith G, Dudbridge F, Hingorani AD, Holmes MV, Casas JP. Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis. Circulation. 2017 Jun 13;135(24):2373-2388. doi: 10.1161/CIRCULATIONAHA.116.026560. Epub 2017 May 12. PubMed PMID: 28500271; PubMed Central PMCID: PMC5515354.
  • Gentry-Maharaj A, Karpinskyj C, Glazer C, Burnell M, Bailey K, Apostolidou S, Ryan A, Lanceley A, Fraser L, Jacobs I, Hunter MS, Menon U. Prevalence and predictors of complementary and alternative medicine/non-pharmacological interventions use for menopausal symptoms within the UK Collaborative Trial of Ovarian Cancer Screening. Climacteric. 2017 Jun;20(3):240-247. doi: 10.1080/13697137.2017.1301919. Epub 2017 Mar 22. PubMed PMID: 28326899; PubMed Central PMCID: PMC5448394.
  • Mariño IP*, Blyuss O*, Ryan A, Gentry-Maharaj A, Timms JF, Dawnay A, Kalsi J, Jacobs I, Menon U*, Zaikin A*. Change-point of multiple biomarkers in women with ovarian cancer. Biomedical Signal Processing and Control. 2017 Mar 31; 33:169-77. * equal contribution (online 8 Dec 2016)
  • Gentry-Maharaj A, Glazer C, Burnell M, Ryan A, Berry H, Kalsi J, Woolas R, Skates SJ, Campbell S, Parmar M, Jacobs I, Menon U. Changing trends in reproductive/lifestyle factors in UK women: descriptive study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMJ Open. 2017 Mar 6;7(3):e011822. doi: 10.1136/bmjopen-2016-011822. PubMed PMID: 28264823; PubMed Central PMCID: PMC5353253.
  • Kazarian A, Blyuss O, Metodieva G, Gentry-Maharaj A, Ryan A, Kiseleva EM, Prytomanova OM, Jacobs IJ, Widschwendter M, Menon U, Timms JF. Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples. Br J Cancer. 2017 Feb 14;116(4):501-508. doi: 10.1038/bjc.2016.433. Epub 2017 Jan 12. PubMed PMID: 28081538; PubMed Central PMCID: PMC5318971.
  • Kiechl S, Schramek D, Widschwendter M, Fourkala EO, Zaikin A, Jones A, Jaeger B, Rack B, Janni W, Scholz C, Willeit J, Weger S, Mayr A, Teschendorff A, Rosenthal A, Fraser L, Philpott S, Dubeau L, Keshtgar M, Roylance R, Jacobs IJ, Menon U, Schett G, Penninger JM. Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer. Oncotarget. 2017 Jan 17;8(3):3811-3825. doi: 10.18632/oncotarget.14013. PubMed PMID: 28002811; PubMed Central PMCID: PMC5354797.
  • Russell MR, D'Amato A, Graham C, Crosbie EJ, Gentry-Maharaj A, Ryan A, Kalsi JK, Fourkala EO, Dive C, Walker M, Whetton AD, Menon U, Jacobs I, Graham RL. Novel risk models for early detection and screening of ovarian cancer. Oncotarget. 2017 Jan 3;8(1):785-797. doi: 10.18632/oncotarget.13648. PubMed PMID: 27903971; PubMed Central PMCID: PMC5352196.
  • Pennington M, Gentry-Maharaj A, Karpinskyj C, Miners A, Taylor J, Manchanda R, Iyer R, Griffin M, Ryan A, Jacobs I, Menon U*, Legood R*. Long-Term Secondary Care Costs of Endometrial Cancer: A Prospective Cohort Study Nested within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). PLoS One. 2016 Nov 9;11(11):e0165539. doi: 10.1371/journal.pone.0165539. PubMed PMID: 27829038; PubMed Central PMCID: PMC5102347. * equal contribution
  • Russell MR, Walker MJ, Williamson AJ, Gentry-Maharaj A, Ryan A, Kalsi J, Skates S, D'Amato A, Dive C, Pernemalm M, Humphryes PC, Fourkala EO, Whetton AD, Menon U, Jacobs I, Graham RL. Protein Z: A putative novel biomarker for early detection of ovarian cancer. Int J Cancer. 2016 Jun 15;138(12):2984-92. doi: 10.1002/ijc.30020. PubMed PMID: 26815306; PubMed Central PMCID: PMC4840324.
  • Fourkala EO, Blyuss O, Field H, Gunu R, Ryan A, Barth J, Jacobs I, Zaikin A, Dawnay A, Menon U. Sex hormone measurements using mass spectrometry and sensitive extraction radioimmunoassay and risk of estrogen receptor negative and positive breast cancer: Case control study in UK Collaborative Cancer Trial of Ovarian Cancer Screening (UKCTOCS). Steroids. 2016 Jun;110:62-9. doi: 10.1016/j.steroids.2016.04.003. Epub 2016 Apr 16. PubMed PMID: 27091764.
  • Jenkinson C, Elliott VL, Evans A, Oldfield L, Jenkins RE, O'Brien DP, Apostolidou S, Gentry-Maharaj A, Fourkala EO, Jacobs IJ, Menon U, Cox T, Campbell F, Pereira SP, Tuveson DA, Park BK, Greenhalf W, Sutton R, Timms JF, Neoptolemos JP, Costello E. Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus. Clin Cancer Res. 2016 Apr 1;22(7):1734-43. doi: 10.1158/1078-0432.CCR-15-0879. Epub 2015 Nov 16. PubMed PMID: 26573598; PubMed Central PMCID: PMC4820087.
  • Thomas DS, Fourkala EO, Apostolidou S, Gunu R, Ryan A, Jacobs I, Menon U, Alderton W, Gentry-Maharaj A, Timms JF. Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples. Br J Cancer. 2015 Jul 14;113(2):268-74. doi: 10.1038/bjc.2015.202. Epub 2015 Jun 2. PubMed PMID: 26035703; PubMed Central PMCID: PMC4506388.
  • Key TJ, Appleby PN, Reeves GK, Travis RC, Brinton LA, Helzlsouer KJ, Dorgan JF, Gapstur SM, Gaudet MM, Kaaks R, Riboli E, Rinaldi S, Manjer J, Hallmans G, Giles GG, Le Marchand L, Kolonel LN, Henderson BE, Tworoger SS, Hankinson SE, Zeleniuch-Jacquotte A, Koenig K, Krogh V, Sieri S, Muti P, Ziegler RG, Schairer C, Fuhrman BJ, Barrett-Connor E, Laughlin GA, Grant EJ, Cologne J, Ohishi W, Hida A, Cauley JA, Fourkala EO, Menon U, Rohan TE, Strickler HD, Gunter MJ; Endogenous Hormones and Breast Cancer Collaborative Group. Steroid hormone measurements from different types of assays in relation to body mass index and breast cancer risk in postmenopausal women: Reanalysis of eighteen prospective studies. Steroids. 2015 Jul;99(Pt A):49-55. doi: 10.1016/j.steroids.2014.09.001. Epub 2014 Oct 7. PubMed PMID: 25304359; PubMed Central PMCID: PMC4502556.
  • Nouretdinov I, Devetyarov D, Vovk V, Burford B, Camuzeaux S, Gentry-Maharaj A, Tiss A, Smith C, Luo ZY, Chervonenkis A, Hallett R, Waterfield M, Cramer R, Timms JF, Jacobs I, Menon U, Gammerman A. Multiprobabilistic prediction in early medical diagnoses. Annals of Mathematics and Artificial Intelligence. 2015 Jun; 74(1-2):203-222. Web of Science ISI:000355747600011
  • Gentry-Maharaj A, Karpinskyj C, Glazer C, Burnell M, Ryan A, Fraser L, Lanceley A, Jacobs I, Hunter MS, Menon U. Use and perceived efficacy of complementary and alternative medicines after discontinuation of hormone therapy: a nested United Kingdom Collaborative Trial of Ovarian Cancer Screening cohort study. Menopause. 2015 Apr;22(4):384-90. doi: 10.1097/GME.0000000000000330. PubMed PMID: 25290539; PubMed Central PMCID: PMC4470524.
  • Bailey K, Ryan A, Apostolidou S, Fourkala E, Burnell M, Gentry-Maharaj A, Kalsi J, Parmar M, Jacobs I, Pikhart H, Menon U. Socioeconomic indicators of health inequalities and female mortality: a nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMC Public Health. 2015 Mar 17;15:253. doi: 10.1186/s12889-015-1609-5. PubMed PMID: 25848938; PubMed Central PMCID: PMC4367890.
  • O'Brien DP, Sandanayake NS, Jenkinson C, Gentry-Maharaj A, Apostolidou S, Fourkala EO, Camuzeaux S, Blyuss O, Gunu R, Dawnay A, Zaikin A, Smith RC, Jacobs IJ, Menon U, Costello E, Pereira SP, Timms JF. Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection. Clin Cancer Res. 2015 Feb 1;21(3):622-31. doi: 10.1158/1078-0432.CCR-14-0365. Epub 2014 Jun 17. PubMed PMID: 24938522; PubMed Central PMCID: PMC4181906.
  • Jenkinson C, Elliott V, Menon U, Apostolidou S, Fourkala OE, Gentry-Maharaj A, Pereira SP, Jacobs I, Cox TF, Greenhalf W, Timms JF, Sutton R, Neoptolemos JP, Costello E. Evaluation in pre-diagnosis samples discounts ICAM-1 and TIMP-1 as biomarkers for earlier diagnosis of pancreatic cancer. J Proteomics. 2015 Jan 15;113:400-2. PubMed PMID: 25316052.
  • Blyuss O, Gentry-Maharaj A, Fourkala EO, Ryan A, Zaikin A, Menon U, Jacobs I, Timms JF. Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset. Biomed Res Int. 2015;2015:681416. doi: 10.1155/2015/681416. Epub 2015 Dec 24. PubMed PMID: 26819954; PubMed Central PMCID: PMC4706857.
  • Timms JF, Arslan-Low E, Kabir M, Worthington J, Gentry-Maharaj A, Camuzeaux S, Sinclair J, Szaub J, Afrough B, Fourkala E-O, Podust V, Kronenberg F, Cubizolles M, Fung ET, Menon U and Jacobs I. Discovery of serum biomarkers of ovarian cancer using complementary proteomic profiling strategies. Proteomics Clinical Applications 2014 Dec;8(11-12):982-93. doi: 10.1002/prca.201400063. Epub 2014 Nov 10.
  • Fourkala E-O*, Burnell M*, Cox C, Ryan A, Salter LC, Gentry-Maharaj A, Parmar M, Jacobs I, Menon U (*joint). Association of skirt size and postmenopausal breast cancer risk in older women: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMJ open 2014 Oct 6;4(9):e005400.
  • Anjum S*, Fourkala E-O*, Zikan M, Wong A, Gentry-Maharaj A, Jones A, Hardy R, Cibula D, Kuh D, Jacobs IJ, Teschendorff AE, Menon U, Widschwendter M (*joint). A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival. Genome medicine 2014 Jun 27;6(6):47.
  • Fraser L, Burnell M, Salter LC, Fourkala E-O, Kalsi J, Ryan A, Gessler S, Gidron Y, Steptoe A, Menon U. Identifying hopelessness in population research: a validation study of two brief measures of hopelessness. BMJ Open 2014 May 30;4(5):e005093.
  • Pedersen JW*, Gentry-Maharaj* A, Nostdal A, Fourkala E-O, Dawnay A, Burnell M, Zaikin A, Burchell J, Papadimitriou JT, Clausen H, Jacobs I, Menon U*, Wandall HH* (*joint). Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case-control study of colorectal cancer in UK collaborative trial of ovarian cancer screening. International journal of cancer Journal international du cancer 2014 May 1;134(9):2180-88.
  • Gentry-Maharaj A, Taylor H, Kalsi J, Ryan A, Burnell M, Sharma A, Apostolidou S, Campbell S, Jacobs I, Menon U. Validity of self-reported hysterectomy: a prospective cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMJ open. 2014;4(3):e004421.
  • Pedersen JW*, Gentry-Maharaj* A, Nostdal A, Fourkala EO, Dawnay A, Burnell M, Zaikin A, Burchell J, Papadimitriou JT, Clausen H, Jacobs I, Menon U*, Wandall HH* (*joint). Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case-control study of colorectal cancer in UK collaborative trial of ovarian cancer screening. International journal of cancer Journal international du cancer. 2014 May 1;134(9):2180-88.
  • O'Brien DP, Sandanayake NS, Jenkinson C, Gentry-Maharaj A, Apostolidou S, Fourkala EO, Camuzeaux S, Blyuss O, Gunu R, Dawnay A, Zaikin A, Smith RC, Jacobs I, Menon U, Costello E, Pereira SP, Timms JF. Serum CA19-9 is significantly up-regulated up to 2 years prior to diagnosis with pancreatic cancer: implications for early disease detection. Clinical cancer research: an official journal of the American Association for Cancer Research. 2014 Jun 17.
  • Fourkala EO*, Burnell M*, Cox C, Ryan A, Salter LC, Gentry-Maharaj A, Parmar M, Jacobs I, Menon U (*joint). Association of skirt size and postmenopausal breast cancer risk in older women: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMJ open. 2014;4(9):e005400.
  • Anjum S*, Fourkala EO*, Zikan M, Wong A, Gentry-Maharaj A, Jones A, Hardy R, Cibula D, Kuh D, Jacobs IJ, Teschendorff AE, Menon U, Widschwendter M (*joint). A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival. Genome medicine. 2014;6(6):47.
  • Jenkinson C, Elliott V, Menon U, Apostolidou S, Fourkala OE, Gentry-Maharaj A, Pereira SP, Jacobs I, Cox TF, Greenhalf W, Timms JF, Sutton R, Neoptolemos JP, Costello E. Evaluation in pre-diagnosis samples discounts ICAM-1 and TIMP-1 as biomarkers for earlier diagnosis of pancreatic cancer. Journal of proteomics. 2014 Oct 12;113C:400-2.
  • Fraser L, Burnell M, Salter LC, Fourkala EO, Kalsi J, Ryan A, Gessler S,Gidron Y, Steptoe A, Menon U. Identifying hopelessness in population research: a validation study of two brief measures of hopelessness. BMJ open 2014;4(5):e005093.
  • Barrett J, Jenkins V, Farewell V, Menon U, Jacobs I, Kilkerr J, Ryan A, Langridge C, Fallowfield L; UKCTOCS trialists. Psychological morbidity associated with ovarian cancer screening: results from more than 23,000 women in the randomised trial of ovarian cancer screening (UKCTOCS). BJOG : an international journal of obstetrics and gynaecology 2014;121(9):1071-9.
  • Gentry-Maharaj A, Fourkala EO, Burnell M, Ryan A, Apostolidou S, Habib M, Sharma A, Parmar M, Jacobs I, Menon U. Concordance of National Cancer Registration with self-reported breast, bowel and lung cancer in England and Wales: a prospective cohort study within the UK Collaborative Trial of Ovarian Cancer Screening. British journal of cancer 2013;109(11):2875-9.
  • Burford B*, Gentry-Maharaj A*, Graham R*, Allen D, Pedersen JW, Nudelman AS, Blixt O, Fourkala EO, Bueti D, Dawnay A, Ford J, Desai R, David L, Trinder P, Acres B, Schwientek T, Gammerman A, Reis CA, Silva L, Osorio H, Hallett R, Wandall HH, Mandel U, Hollingsworth MA, Jacobs I, Fentiman I, Clausen H, Taylor-Papadimitriou J*, Menon U*, Burchell JM* (*joint). Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer. British journal of cancer. 2013 May 28;108(10):2045-55.
  • Pedersen JW*, Gentry-Maharaj A*, Fourkala E-O, Dawnay A, Burnell M, Zaikin A, Pedersen AE, Jacobs I, Menon U**, Wandall H** Early detection of cancer in the general population - a blinded case control study of p53 auto-antibodies in colorectal cancer. Br J Cancer. 2013 Jan 15;108(1):107-14.
  • Devetyarov D, Nouretdinov I, Burford B, Camuzeaux S, Gentry-Maharaj A, Tiss A, Smith C, Luo Z, Chervonenkis A, Hallett R, Vovk V, Waterfield M, Cramer R, Timms JF, Sinclair J, Menon U, Jacobs I, Gammerman A Conformal predictors in early diagnostics of ovarian and breast cancers. Progress in Artificial Intelligence.Volume 1, Number 3 (2012), 245-257
  • Fourkala E-O, Gentry-Maharaj A, Burnell M, Ryan A, Manchanda R, Dawnay A, Jacobs I, Widschwendter M, Menon U. Histological confirmation of breast cancer registration and self-reporting in England and Wales: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening. Br J Cancer 2012;106(12):1910-6.
  • Hunter M, Gentry-Maharaj A, Lanceley A, Fraser L, Burnell M, Ryan A, Fraser L, Jacobs I, Menon U. Prevalence, frequency and problem rating of hot flushes persist in older postmenopausal women: impact of age, body mass index, hysterectomy, hormone therapy use, lifestyle and mood in a cross-sectional cohort study of 10,418 British women aged 54-65. BJOG : an international journal of obstetrics and gynaecology, 2012. 119(1): p. 40-50
  • Hamajima N, Hirose K, Tajima K, Rohan T, Friedenreich CM, Calle EE, Gapstur SM, Patel AV, Coates RJ, Liff JM, Talamini R, Chantarakul N, Koetsawang S, Rachawat D, Marcou Y, Kakouri E, Duffy SW, Morabia A, Schuman L, Stewart W, Szklo M, Coogan PF, Palmer JR, Rosenberg L, Band P, Coldman AJ, Gallagher RP, Hislop TG, Yang P, Cummings SR, Canfell K, Sitas F, Chao P, Lissowska J, Horn-Ross PL, John EM, Kolonel LM, Nomura AMY, Ghiasvand R, Hu J, Johnson KC, Mao Y, Beral V, Bull D, Callaghan K, Crossley B, Goodill A, Green J, Hermon C, Key T, Lindgard I, Liu B, Pirie K, Reeves G, Collins R, Doll R, Peto R, Bishop T, Fentiman IS, De Sanjose S, Gonzalez CA, Lee N, Marchbanks P, Ory HW, Peterson HB, Wingo P, Ebeling K, Kunde D, Nishan P, Hopper JL, Eliassen H, Hankinson S, Gajalakshmi V, Martin N, Pardthaisong T, Silpisornkosol S, Theetranont C, Boosiri B, Chutivongse S, Jimakorn P, Virutamasen P, Wongsrichanalai C, Neugut A, Santella R, Baines CJ, Kreiger N, Miller AB, Wall C, Tjonneland A, Jorgensen T, Stahlberg C, Pedersen AT, Flesch-Janys D, Hakansson N, Cauley J, Heuch I, Adami HO, Persson I, Weiderpass E, Magnusson C, Chang-Claude J, Kaaks R, McCredie M, Paul C, Skegg DCG, Spears GFS, Iwasaki M, Tsugane S, Anderson G, Daling JR, Hampton J, Hutchinson WB, Li CI, Malone K, Mandelson M, Newcomb P, Noonan EA, Ray RM, Stanford JL, Tang MTC, Thomas DB, Weiss NS, White E, Izquierdo A, Viladiu P, Fourkala EO, Jacobs I, Menon U, Ryan A, Cuevas HR, Ontiveros P, Palet A, Salazar SB, Aristizabal N, Cuadros A, Tryggvadottir L, Tulinius H, Riboli E, Andrieu N, Bachelot A, Le MG, Bremond A, Gairard B, Lansac J, Piana L, Renaud R, Clavel-Chapelon F, Fournier A, Touillaud M, Mesrine S, Chabbert-Buffet N, Boutron-Ruault MC, Wolk A, Torres-Mejia G, Franceschi S, Romieu I, Boyle P, Lubin F, Modan B, Ron E, Wax Y, Friedman GD, Hiatt RA, Levi F, Kosmelj K, Primic-Zakelj M, Ravnihar B, Stare J, Ekbom A, Erlandsson G, Beeson WL, Fraser G, Peto J, Hanson RL, Leske MC, Mahoney MC, Nasca PC, Varma AO, Weinstein AL, Hartman ML, Olsson H, Goldbohm RA, van den Brandt PA, Palli D, Teitelbaum S, Apelo RA, Baens J, de la Cruz JR, Javier B, Lacaya LB, Ngelangel CA, La Vecchia C, Negri E, Marubini E, Ferraroni M, Pike MC, Gerber M, Richardson S, Segala C, Gatei D, Kenya P, Kungu A, Mati JG, Brinton LA, Freedman M, Hoover R, Schairer C, Ziegler R, Banks E, Spirtas R, Lee HP, Rookus MA, van Leeuwen FE, Schoenberg JA, Graff-Iversen S, Selmer R, Jones L, McPherson K, Neil A, Vessey M, Yeates D, Mabuchi K, Preston D, Hannaford P, Kay C, McCann SE, Rosero-Bixby L, Gao YT, Jin F, Yuan J-M, Wei HY, Yun T, Zhiheng C, Berry G, Cooper Booth J, Jelihovsky T, MacLennan R, Shearman R, Hadjisavvas A, Kyriacou K, Loisidou M, Zhou X, Wang Q-S, Kawai M, Minami Y, Tsuji I, Lund E, Kumle M, Stalsberg H, Shu XO, Zheng W, Monninkhof EM, Onland-Moret NC, Peeters PHM, Katsouyanni K, Trichopoulou A, Trichopoulos D, Tzonou A, Baltzell KA, Dabancens A, Martinez L, Molina R, Salas O, Alexander FE, Anderson K, Folsom AR, Gammon MD, Hulka BS, Millikan R, Chilvers CED, Lumachi F, Bain C, Schofield F, Siskind V, Rebbeck TR, Bernstein LR, Enger S, Haile RW, Paganini-Hill A, Ross RK, Ursin G, Wu AH, Yu MC, Ewertz M, Clarke EA, Bergkvist L, Anderson GL, Gass M, O'Sullivan MJ, Kalache A, Farley TMM, Holck S, Meirik O, Fukao A. Collaborative Group on Hormonal Factors in Breast Cancer. Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies. The Lancet. Oncology 2012;13(11):1141-51
  • Fourkala EO, Zaikin A, Burnell M, Gentry-Maharaj A, Ford J, Gunu R, Soromani C, Hasenbrink G, Jacobs I, Dawnay A, Widschwendter M, Lichtenberg-Fraté H, Menon U. Association of serum sex steroid receptor bioactivity and sex steroid hormones with breast cancer risk in postmenopausal women. Endocrine-related cancer 2012;19(2):137-47.
  • Timms JF, Menon U, Devetyarov D, Tiss A, Camuzeaux S, McCurrie K, Nouretdinov I, Burford B, Smith C, Gentry-Maharaj A, Hallett R, Ford J, Luo Z, Vovk V, Gammerman A, Cramer R and Jacobs I. Early detection of ovarian cancer in samples pre-diagnosis using CA125 and MALDI-MS peaks. Cancer Genomics Proteomics 2011;8(6):289-305.
  • Jacobs I, Gentry-Maharaj A, Burnell M, Manchanda R, Singh N, Sharma A, Ryan A, Seif M, Amso NN, Turner G, Brunell C, Fletcher G, Rangar R, Ford K, Godfrey K, Lopes A, Oram D, Herod J, Williamson K, Scott I, Jenkins H, Mould T, Woolas R, Murdoch J, Dobbs S, Leeson S, Cruickshank D, Skates SJ, Fallowfield L, Parmar M, Campbell S, Menon U. Sensitivity of transvaginal ultrasound screening for endometrial cancer in postmenopausal women: a case-control study within the UKCTOCS cohort. The lancet oncology, 2011. 12(1): p. 38-48.
  • Gammerman A, Vovk V, Burford B, Nouretdinov I, Luo Z, Chervonenkis A, Waterfield M, Cramer R, Tempst P, Villanueva J, Kabir M, Camuzeaux S, Timms J, Menon U and Jacobs I. Serum Proteomic Abnormality Predating Screen Detection of Ovarian Cancer. Comput J 2009;52(3):326-33.
  • Widschwendter M, Lichtenberg-Frate H, Hasenbrink G, Schwarzer S, Dawnay A, Lam A, Menon U, Apostolidou S, Raum E, Stegmaier C, Jacobs IJ, Brenner H. Serum oestrogen receptor alpha and beta bioactivity are independently associated with breast cancer: a proof of principle study. British journal of cancer 2009;101(1):160-5.
  • Menon U, Burnell M, Sharma A, Gentry-Maharaj A, Fraser L, Ryan A, Parmar M, Hunter M, Jacobs I. Decline in use of hormone therapy among postmenopausal women in the United Kingdom. Menopause, 2007. 14(3 Pt 1): p. 462-7.
  • Timms JF, Arslan-Low E, Gentry-Maharaj A, Luo Z, T'Jampens D, Podust VN, Ford J, Fung ET, Gammerman A, Jacobs I, Menon, U. Preanalytic influence of sample handling on SELDI-TOF serum protein profiles. Clinical chemistry, 2007. 53(4): p. 645-56.

Grouped by methodologies / technologies used

  • Widschwendter M, Zikan M, Wahl B, Lempiainen H, Paprotka T, Evans I, Jones A, Ghazali S, Reisel D, Eichner J, Rujan T, Yang Z, Teschendorff AE, Ryan A, Cibula D, Menon U, Wittenberger T. The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer. Genome medicine. 2017;9(1):116. PMCID: PMC5740748
  • Widschwendter M, Evans I, Jones A, Ghazali S, Reisel D, Ryan A, Gentry-Maharaj A, Zikan M, Cibula D, Eichner J, Alunni-Fabbroni M, Koch J, Janni WJ, Paprotka T, Wittenberger T, Menon U, Wahl B, Rack B, Lempiainen H. Methylation patterns in serum DNA for early identification of disseminated breast cancer. Genome medicine. 2017;9(1):115. https://doi.org/10.1186/s13073-017-0500-7
  • Anjum S, Fourkala EO, Zikan M, Wong A, Gentry-Maharaj A, Jones A, Hardy R, Cibula D, Kuh D, Jacobs IJ, Teschendorff AE, Menon U, Widschwendter M. A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival. Genome medicine. 2014;6(6):47. https://doi.org/10.1186/gm567
  • Borges MC, Barros AJD, Ferreira DLS, Casas JP, Horta BL, Kivimaki M, Kumari M, Menon U, Gaunt TR, Ben-Shlomo Y, Freitas DF, Oliveira IO, Gentry-Maharaj A, Fourkala E, Lawlor DA, Hingorani AD. Metabolic Profiling of Adiponectin Levels in Adults. Mendelian Randomization Analysis. 2017;10(6). https://doi.org/10.1161/CIRCGENETICS.117.001837
  • Yang WL, Gentry-Maharaj A, Simmons AR, Ryan A, Fourkala EO, Lu Z, Baggerly KA, Zhao Y, Lu K, Bowtell DDL, Jacobs I, Skates SJ, He WW, Menon U, Bast RC. Elevation of TP53 Autoantibody Prior to CA125 in Preclinical Invasive Epithelial Ovarian Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2017. https://doi.org/10.1158/1078-0432.CCR-17-0284
  • Pedersen JW, Gentry-Maharaj A, Nostdal A, Fourkala EO, Dawnay A, Burnell M, Zaikin A, Burchell J, Papadimitriou JT, Clausen H, Jacobs I, Menon U, Wandall HH. Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case-control study of colorectal cancer in UK collaborative trial of ovarian cancer screening. International journal of cancer. 2014;134(9):2180-88. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234004/
  • Burford B, Gentry-Maharaj A, Graham R, Allen D, Pedersen JW, Nudelman AS, Blixt O, Fourkala EO, Bueti D, Dawnay A, Ford J, Desai R, David L, Trinder P, Acres B, Schwientek T, Gammerman A, Reis CA, Silva L, Osorio H, Hallett R, Wandall HH, Mandel U, Hollingsworth MA, Jacobs I, Fentiman I, Clausen H, Taylor-Papadimitriou J, Menon U, Burchell JM. Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer. British journal of cancer. 2013;108(10):2045-55.Burford B, Gentry-Maharaj A, Graham R, Allen D, Pedersen JW, Nudelman AS, et al. Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer. British journal of cancer 2013 May 28;108(10):2045-55. https://doi.org/10.1038/bjc.2013.214
  • Pedersen JW, Gentry-Maharaj A, Fourkala EO, Dawnay A, Burnell M, Zaikin A, Pedersen AE, Jacobs I, Menon U, Wandall HH. Early detection of cancer in the general population: a blinded case-control study of p53 autoantibodies in colorectal cancer. British journal of cancer. 2013;108(1):107-14. https://doi.org/10.1038/bjc.2012.517
  • Fourkala EO, Blyuss O, Field H, Gunu R, Ryan A, Barth J, Jacobs I, Zaikin A, Dawnay A, Menon U. Sex hormone measurements using mass spectrometry and sensitive extraction radioimmunoassay and risk of estrogen receptor negative and positive breast cancer: Case control study in UK Collaborative Cancer Trial of Ovarian Cancer Screening (UKCTOCS). Steroids. 2016;110:62-9 https://doi.org/10.1016/j.steroids.2016.04.003
  • Key TJ, Appleby PN, Reeves GK, Travis RC, Brinton LA, Helzlsouer KJ, Dorgan JF, Gapstur SM, Gaudet MM, Kaaks R, Riboli E, Rinaldi S, Manjer J, Hallmans G, Giles GG, Le Marchand L, Kolonel LN, Henderson BE, Tworoger SS, Hankinson SE, Zeleniuch-Jacquotte A, Koenig K, Krogh V, Sieri S, Muti P, Ziegler RG, Schairer C, Fuhrman BJ, Barrett-Connor E, Laughlin GA, Grant EJ, Cologne J, Ohishi W, Hida A, Cauley JA, Fourkala EO, Menon U, Rohan TE, Strickler HD, Gunter MJ. Steroid hormone measurements from different types of assays in relation to body mass index and breast cancer risk in postmenopausal women: Reanalysis of eighteen prospective studies. Steroids. 2015;99(Pt A):49-55. https://doi.org/10.1016/j.steroids.2014.09.001
  • Fourkala EO, Zaikin A, Burnell M, Gentry-Maharaj A, Ford J, Gunu R, Soromani C, Hasenbrink G, Jacobs I, Dawnay A, Widschwendter M, Lichtenberg-Frate H, Menon U. Association of serum sex steroid receptor bioactivity and sex steroid hormones with breast cancer risk in postmenopausal women. Endocr Relat Cancer. 2012;19(2):137-47. https://doi.org/10.1530/ERC-11-0310
  • Krishnan S, Whitwell HJ, Cuenco J, Gentry-Maharaj A, Menon U, Pereira SP, Gaspari M, Timms JF. Evidence of Altered Glycosylation of Serum Proteins Prior to Pancreatic Cancer Diagnosis. International journal of molecular sciences. 2017;18(12). https://doi.org/10.3390/ijms18122670
  • Jenkinson C, Elliott VL, Evans A, Oldfield L, Jenkins RE, O'Brien DP, Apostolidou S, Gentry-Maharaj A, Fourkala EO, Jacobs IJ, Menon U, Cox T, Campbell F, Pereira SP, Tuveson DA, Park BK, Greenhalf W, Sutton R, Timms JF, Neoptolemos JP, Costello E. Decreased Serum Thrombospondin-1 Levels in Pancreatic Cancer Patients Up to 24 Months Prior to Clinical Diagnosis: Association with Diabetes Mellitus. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016;22(7):1734-43 https://doi.org/10.1158/1078-0432.CCR-15-0879
  • Russell MR, Walker MJ, Williamson AJ, Gentry-Maharaj A, Ryan A, Kalsi J, Skates S, D'Amato A, Dive C, Pernemalm M, Humphryes PC, Fourkala EO, Whetton AD, Menon U, Jacobs I, Graham RL. Protein Z: A putative novel biomarker for early detection of ovarian cancer. International journal of cancer. 2016;138(12):2984-92. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840324/
  • Russell MR, D'Amato A, Graham C, Crosbie EJ, Gentry-Maharaj A, Ryan A, Kalsi JK, Fourkala EO, Dive C, Walker M, Whetton AD, Menon U, Jacobs I, Graham RL. Novel risk models for early detection and screening of ovarian cancer. Oncotarget. 2016. https://doi.org/10.18632/oncotarget.13648
  • Jenkinson C, Elliott V, Menon U, Apostolidou S, Fourkala OE, Gentry-Maharaj A, Pereira SP, Jacobs I, Cox TF, Greenhalf W, Timms JF, Sutton R, Neoptolemos JP, Costello E. Evaluation in pre-diagnosis samples discounts ICAM-1 and TIMP-1 as biomarkers for earlier diagnosis of pancreatic cancer. J Proteomics. 2015;113:400-2. https://doi.org/10.1016/j.jprot.2014.10.001
  • Thomas DS, Fourkala EO, Apostolidou S, Gunu R, Ryan A, Jacobs I, Menon U, Alderton W, Gentry-Maharaj A, Timms JF. Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples. British journal of cancer. 2015;113(2):268-74. https://doi.org/10.1038/bjc.2015.202
  • Nouretdinov I, Devetyarov D, Vovk V, Burford B, Camuzeaux S, Gentry-Maharaj A, Tiss A, Smith C, Luo Z, Chervonenkis A, Hallett R, Waterfield M, Cramer R, Timms JF, Jacobs I, Menon U, Gammerman A. Multiprobabilistic prediction in early medical diagnoses. Annals of Mathematics and Artificial Intelligence. 2015;74(1):203-22. https://doi.org/10.1007/s10472-013-9367-5
  • Timms JF, Arslan-Low E, Kabir M, Worthington J, Camuzeaux S, Sinclair J, Szaub J, Afrough B, Podust VN, Fourkala EO, Cubizolles M, Kronenberg F, Fung ET, Gentry-Maharaj A, Menon U, Jacobs I. Discovery of serum biomarkers of ovarian cancer using complementary proteomic profiling strategies. Proteomics Clin Appl. 2014;8(11-12):982-93 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737403/
  • Timms JF, Menon U, Devetyarov D, Tiss A, Camuzeaux S, McCurrie K, Nouretdinov I, Burford B, Smith C, Gentry-Maharaj A, Hallett R, Ford J, Luo Z, Vovk V, Gammerman A, Cramer R, Jacobs I. Early detection of ovarian cancer in samples pre-diagnosis using CA125 and MALDI-MS peaks. Cancer Genomics Proteomics. 2011;8(6):289-305. http://cgp.iiarjournals.org/content/8/6/289.long
  • Blyuss O, Burnell M, Ryan A, Gentry-Maharaj A, Mariño IP, Kalsi J, Manchanda R, Timms JF, Parmar M, Skates SJ, Jacobs I, Zaikin A, Menon U. Comparison of Longitudinal CA125 Algorithms as a First-Line Screen for Ovarian Cancer in the General Population. Clin Cancer Res. 2018 Oct 1;24(19):4726-4733. https://doi.org/10.1158/1078-0432.CCR-18-0208

  • Mariño IP, Blyuss O, Ryan A, Gentry-Maharaj A, Timms JF, Dawnay A, Kalsi J, Jacobs I, Menon U, Zaikin A. Change-point of multiple biomarkers in women with ovarian cancer. Biomedical Signal Processing and Control. 2017;33:169-77. https://doi.org/10.1016/j.bspc.2016.11.015

  • Kazarian A, Blyuss O, Metodieva G, Gentry-Maharaj A, Ryan A, Kiseleva EM, Prytomanova OM, Jacobs IJ, Widschwendter M, Menon U, Timms JF. Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples. British journal of cancer. 2017;116(4):501-8 https://doi.org/10.1038/bjc.2016.433
  • Russell MR, Graham C, D'Amato A, Gentry-Maharaj A, Ryan A, Kalsi JK, Ainley C, Whetton AD, Menon U, Jacobs I, Graham RLJ. A combined biomarker panel shows improved sensitivity for the early detection of ovarian cancer allowing the identification of the most aggressive type II tumours. British journal of cancer. 2017;117(5):666-74. https://doi.org/10.1038/bjc.2017.199
  • O'Brien DP, Sandanayake NS, Jenkinson C, Gentry-Maharaj A, Apostolidou S, Fourkala EO, Camuzeaux S, Blyuss O, Gunu R, Dawnay A, Zaikin A, Smith RC, Jacobs IJ, Menon U, Costello E, Pereira SP, Timms JF. Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015;21(3):622-31. https://doi.org/10.1158/1078-0432.CCR-14-0365
  • Blyuss O, Gentry-Maharaj A, Fourkala EO, Ryan A, Zaikin A, Menon U, Jacobs I, Timms JF. Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset. BioMed research international. 2015;2015:681416. https://doi.org/10.1155/2015/681416
  • Trembling PM, Apostolidou, S., Gentry-Maharaj, A., Parkes, J., Ryan, A., Tanwar, S., Burnell M., Menon, U., Rosenberg W.M. Association between skirt size and chronic liver disease in post-menopausal women: a prospective cohort study within the United Kingdom Trial of Ovarian Cancer Screening (UKCTOCS). BMC public health. 2018. https://doi.org/10.1186/s12889-018-5308-x.
  • Trembling PM, Apostolidou S, Gentry-Maharaj A, Parkes J, Ryan A, Tanwar S, Burnell M, Jacobs I, Menon U, Rosenberg WM. Risk of chronic liver disease in post-menopausal women due to body mass index, alcohol and their interaction: a prospective nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMC public health. 2017;17(1):603. https://doi.org/10.1186/s12889-017-4518-y
  • Stott W, Campbell S, Franchini A, Blyuss O, Zaikin A, Ryan A, Jones C, Gentry-Maharaj A, Fletcher G, Kalsi J, Skates S, Parmar M, Amso N, Jacobs I, Menon U. Self-reported transvaginal ultrasound visualization of normal ovaries in postmenopausal women is not reliable: results of expert review of archived images in UKCTOCS. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2017. http://europepmc.org/abstract/med/28796383
  • Gentry-Maharaj A, Karpinskyj C, Glazer C, Burnell M, Bailey K, Apostolidou S, Ryan A, Lanceley A, Fraser L, Jacobs I, Hunter MS, Menon U. Prevalence and predictors of complementary and alternative medicine/non-pharmacological interventions use for menopausal symptoms within the UK Collaborative Trial of Ovarian Cancer Screening. Climacteric. 2017;20(3):240-7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448394/
  • Gentry-Maharaj A, Glazer C, Burnell M, Ryan A, Berry H, Kalsi J, Woolas R, Skates SJ, Campbell S, Parmar M, Jacobs I, Menon U. Changing trends in reproductive/lifestyle factors in UK women: descriptive study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMJ open. 2017;7(3):e011822. http://bmjopen.bmj.com/content/7/3/e011822
  • Pennington M, Gentry-Maharaj A, Karpinskyj C, Miners A, Taylor J, Manchanda R, Iyer R, Griffin M, Ryan A, Jacobs I, Menon U, Legood R. Long-Term Secondary Care Costs of Endometrial Cancer: A Prospective Cohort Study Nested within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). PloS one. 2016;11(11):e0165539. https://doi.org/10.1371/journal.pone.0165539
  • Gentry-Maharaj A, Karpinskyj C, Glazer C, Burnell M, Ryan A, Fraser L, Lanceley A, Jacobs I, Hunter MS, Menon U. Use and perceived efficacy of complementary and alternative medicines after discontinuation of hormone therapy: a nested United Kingdom Collaborative Trial of Ovarian Cancer Screening cohort study. Menopause. 2015;22(4):384-90. https://doi.org/10.1097/GME.0000000000000330
  • Bailey K, Ryan A, Apostolidou S, Fourkala E, Burnell M, Gentry-Maharaj A, Kalsi J, Parmar M, Jacobs I, Pikhart H, Menon U. Socioeconomic indicators of health inequalities and female mortality: a nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMC public health. 2015;15:253. https://doi.org/10.1186/s12889-015-1609-5
  • Gentry-Maharaj A, Taylor H, Kalsi J, Ryan A, Burnell M, Sharma A, Apostolidou S, Campbell S, Jacobs I, Menon U. Validity of self-reported hysterectomy: a prospective cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMJ open. 2014;4(3):e004421. https://doi.org/10.1136/bmjopen-2013-004421
  • Fraser L, Burnell M, Salter LC, Fourkala EO, Kalsi J, Ryan A, Gessler S, Gidron Y, Steptoe A, Menon U. Identifying hopelessness in population research: a validation study of two brief measures of hopelessness. BMJ open. 2014;4(5):e005093. http://dx.doi.org/10.1136/bmjopen-2014-005093
  • Fourkala EO, Burnell M, Cox C, Ryan A, Salter LC, Gentry-Maharaj A, Parmar M, Jacobs I, Menon U. Association of skirt size and postmenopausal breast cancer risk in older women: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). BMJ open. 2014;4(9):e005400. http://dx.doi.org/10.1136/bmjopen-2014-005400
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