Ovarian & Endometrial cancer

Ovarian cancer is the fifth most common cancer in women. The prognosis of ovarian cancer is poor since women are commonly diagnosed with late stage disease i.e. stage III/IV, for which 5-year survival rates are around 27% and 16%.  Better non-invasive tests for early detection of ovarian cancer are urgently required to reduce mortality due to this disease. Our group has a major interest in identifying novel biomarkers and factors that could be used for risk stratification/ screening and on that basis we have set up several internal studies and external collaborations.

Projects:

Investigators Martin Widschwendter, Shazia Anjum, Alison Jones, A Wong (UCL); David Cibula (Charles University Hospital, Prague, Czech Republic), Ian Jacobs, Usha Menon, (UCL)
Funders EU FP7
Investigators Joy Burchell, Joyce Taylor-Papadimitriou (KCL, London), Henrik Clausen (University of Copenhagen, Copenhagen); Bruce Acres (Transgene, Strasbourg, Germany); Tilo Schwientek (University of Cologne, Cologne, Germany)
Funders EU FP7
Investigators Usha Menon, Aleksandra Gentry-Maharaj (UCL), Steve Skates (MGH, USA), Ian Jacobs (UCL, UNSW)
Funders
  • CRUK
  • Eve Appeal
Investigators Rainer Cramer (Reading University), Mike Waterfield (UCL), Alex Gammerman (RHUL), Usha Menon (UCL), Ian Jacobs (UCL) 
Funders

MRC

Investigators Ian Jacobs (UCL), Simon Gayther, Susan Ramus (USC, Los Angeles, USA); Alexey Zaikin, Usha Menon, John Timms (UCL); Steve Skates (MGH and Harvard Medical School, Boston, USA); Antonis Antoniou (Cambridge University, UK)
Funders
  • CRUK
  • Eve Appeal
Investigators Sudha Sundar (Birmingham Univ), Usha Menon, Aleksandra Gentry-Maharaj (UCL)
Funders

NIHR

Investigators Robert Bast, Keith Baggerly, Zheng Zhang (MD Anderson Cancer Centre, Houston, Texas, USA); Steven Skates (Harvard, Boston, USA)
Funders

CPRIT grant “Texas Cancer Diagnostics Pipeline Consortium” 

Investigators Nicole Urban (Fred Hutch Cancer Centre, Seattle, USA), Usha Menon (UCL), Ian Jacobs (UCL)
Funders

Spore grant NIH, USA

Investigators Anna Lokshin (University of Pittsburgh, USA), Usha Menon (UCL), Ian Jacobs (UCL)  
Funders

RO1, NIH, USA